Chelsea's four-game winning run across all competitions was brought to an end before the international break as Tottenham's North London rivals Arsenal beat the Blues 1-0 at the Emirates Stadium on March 16.

Mikel Merino's first-half header condemned Chelsea to their third Premier League defeat in five matches and Enzo Maresca's side are now clinging on to a top-four place, as they sit just one point above Manchester City in fourth and two clear of sixth-placed Newcastle United - who have a game in hand, while Brentford down in 11th are only eight points behind with nine games still left to play.

Chelsea, who are seeking to avoid a third successive campaign finishing outside the Premier League's top five, currently boast the finest of advantages in the hotly-contested battle to secure Champions League football for next season and are now preparing for three top-flight fixtures against bottom-half opposition, as well as their two-legged Conference League quarter-final tie with Legia Warsaw later this month.

The West Londoners will welcome a return to Stamford Bridge where they have won each of their last four Premier League games, keeping a clean sheet in their last two against Southampton (4-0) and Leicester (1-0) - only once in the last five seasons have Chelsea won three home matches in a row without conceding, doing so from April to May 2024 in a run that included a 2-0 win over Spurs.

Chelsea will fancy their chances of success on Thursday, as they have won more PL games (36) and scored more PL goals (120) against Tottenham than they have versus any other opponent. In fact, only three teams have scored more goals against a side in the division than the 120 Chelsea have netted against Spurs (Arsenal vs. Everton, Manchester United vs. Everton, Liverpool vs. Newcastle - all 124).

Like Chelsea, Tottenham were unable to claim maximum points in their final game before the international break and instead suffered their 15th Premier League defeat of the season at the hands of Fulham.

Second-half strikes from Rodrigo Muniz and ex-Spurs man Ryan Sessegnon condemned the Lilywhites to a 2-0 defeat at Craven Cottage, leaving them languishing in 14th place in the Premier League table and 10 points behind the top half.

Europa League glory is seemingly the only saving grace for Ange Postecoglou, whose Tottenham future has come under the microscope once again following an "unacceptable" loss at Fulham. He is now facing unwanted history, as defeat at Chelsea on Thursday would see the Greek-Australian become the first-ever Spurs manager to lose his first four league meetings against the Blues.

No team has earned fewer Premier League points in London derbies this season than Tottenham (10, level with Brentford), who have lost five out of nine such matches (W3 D1). Only in 1987-88, 1989-90, 2003-04 (all six) and 2004-05 (seven) have Spurs ever suffered more London derby defeats in a league campaign.

Tottenham are bidding to win their first game at Stamford Bridge since a 3-1 success in April 2018, but they head into Thursday's contest having lost eight of their 14 top-flight away matches this term, with only Leicester (10) and Southampton (12) having lost more - not since 2008-09 have the Lilywhites suffered more away defeats in a single league season (11).

Chelsea trio Mykhaylo Mudryk (suspended), Marc Guiu and Omari Kellyman (both hamstring) all remain unavailable for selection, but Cole Palmer, Nicolas Jackson and Noni Madueke could be fit to return to the matchday squad as they have all taken part in training.

The potential return of both Palmer and Jackson could see Pedro Neto move from a makeshift central role over to the right flank, while Jadon Sancho and Christopher Nkunku may battle for a start on the left side of attack.

Reece James played in midfield against Arsenal, but he could revert to right-back with Wesley Fofana potentially moved across into the heart of the defence alongside Levi Colwill, while Maresca will decide whether to stick with goalkeeper Robert Sanchez, who has started three of Chelsea's last four games in all competitions, or recall Filip Jorgensen between the sticks.

As for Tottenham, Radu Dragusin remains out with a season-ending ACL injury, but Postecoglou could be boosted by the return of Lucas Bergvall (illness), Dejan Kulusevski (foot), Kevin Danso (hamstring) and Richarlison (calf) who will all be assessed ahead of kickoff.

Should Danso not be fit to start, Cristian Romero could link arms with Micky van de Ven at centre-back, while Postecoglou will weigh up whether to start in-form Djed Spence ahead of either Pedro Porro or Destiny Udogie at right-back or left-back respectively.

Captain Son Heung-min has started as a substitute in each of last three Premier League games, but the South Korean could be recalled to start on the left flank at the expense of Mathys Tel, while James Maddison, Pape Matar Sarr and Wilson Odobert will also be pushing for a return to the first XI.

Chelsea possible starting lineup:

Sanchez; James, Fofana, Colwill, Cucurella; Caicedo, Fernandez; Neto, Palmer, Sancho; Jackson

Tottenham Hotspur possible starting lineup:

Vicario; Porro, Romero, Van de Ven, Spence; Sarr, Bentancur, Maddison; Johnson, Solanke, Son